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KMID : 0360220160570101592
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Journal of the Korean Ophthalmological Society
2016 Volume.57 No. 10 p.1592 ~ p.1597
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Comparison of Related Factors between Twins in Which Premature of Retinopathy Developed on One Twin
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Lim Jae-Wan
Yoo Jae-Ho
Lee Seung-Uk
Lee Sang-Joon
Nam Ki-Yup
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Abstract
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Purpose: To analyze related factors of retinopathy of prematurity by comparing between premature twins in which retinopathy developed on one twin.
Methods: A retrospective survey consisting of 13 premature twins in which retinopathy of prematurity (stage 1 or more) developed on one twin was performed. All twins were born in Kosin University Gospel Hospital. The twins were separated into two groups according to whether they had retinopathy of prematurity: the retinopathy of prematurity (ROP) group and non-ROP group. The twins’ gestational age, weight, sex, Apgar score, treatments, blood tests, and neonatal complications were investigated.
Results: There were no significant differences between the twins except platelet count and aspartate aminotransferase. Platelet count was 191 (±46) ⅹ103/μL in the ROP group and 240 (±77) ⅹ103/μL in the non-ROP group, a significant difference (p = 0.046). Aspartate aminotransferase was 36 (±26.6) IU/L in the ROP group and 22 (±5.9) IU/L in the non-ROP group, a significant difference (p = 0.019).
Conclusions: In conclusion, we found platelet count and aspartate aminotransferase to be significant factors related to development of retinopathy of prematurity. It is thought that these factors should be considered when screening for ROP, although a larger prospective study is be needed before the results can be applied in clinical practice.
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KEYWORD
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Aspartate aminotransferase, Platelet, Retinopathy of prematurity (ROP), Twin
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